Experimental Arteriosclerosis

Spontaneous Arteriosclerosis in Rabbits

Prevention of Heart Disease by Controlling Risk Factors

For a long period of time some different hypothesis have been published about arteriosclerosis but none of them has discovered the pathogenesis and effective treat­ment of this entity. By elemination of risk factors it is not clear that the disease process stops or reverses. Pre­ventiona and treatment of risk factors should start before manifestation of arteriosclerosis sympthoms. The result of...

Effect of olive leaf, mulberry leaf and fenugreek seed extract on plasma cholesterols and fatty streaks at aorta wall on hypercholestrolemic rabbit

Introduction: dyslipidemia is one of the most important risk factors that cause arteriosclerosis in the coronary artery. The aim of this study was to investigate olive and mulberry leaf , fenugreek seed– dyethylether extract on plasma lipid levels and arteriosclerosis plaques. Materials & Methods: 45 white male rabbits divided into nine groups of five at 22 ±1C.The first and second group were ...

Tadalafil attenuates graft arteriosclerosis of aortic transplant in a rat model

Objective(s): Tadalafil can restore endothelial function and treat atherosclerosis. However, the effect of tadalafil on transplant arteriosclerosis remains unclear. In this study, we explore the effects of tadalafil on allograft vasculopathy. Materials and Methods: Male Brow-Norway rats supplied aorta grafts for Male Lewis rats. All recipients were divided into 3 groups: saline as placebo (con...

Vitamin B6 and arteriosclerosis.

In 1949, Rinehart and Greenberg reported that marked arteriosclerosis occurs in vitamin-B6-deficient monkeys. The present study investigates the relationship between vitamin B6 and arteriosclerosis and summarizes the results. I found that thrombogenesis, disorder of collagen metabolism and production of free radicals may be the processes that cause arteriosclerosis in human and experimental ani...

The abnormal serum lipid pattern in patients with coronary arteriosclerosis.

Studies in experimental arteriosclerosis have indicated that the relative level of serum lipid phosphorus may be as significant a factor as the absolute level of serum cholesterol in the production of arterial lesions. For this reason, the serum lipid pattern of 82 patients with coronary arteriosclerosis has been compared with that of 112 healthy adults. An elevation of the serum cholesterol, s...